Treating Aggressive Brain Tumors With Less Side Effects
One problem when treating brain diseases is that less than 1% of the IV administered drugs actually make it to the brain. Even when applied directly into the brain, these biological drugs rapidly leave the brain and start accumulating in the body.
InCephalo’s compartment locked technology (CLock) creates for the first time tailor-made biological drugs for local treatment of the brain. The CLocked drugs stay in the desired compartment, and if they leak, they are rapidly degraded.
This significantly reduces the drugs’ overall exposure to the body and allows for a higher local dosing window.